both CD and VD was coagulase negative Staphylococcus. Adjusting for confounders, CD remained an independent risk factor for positive blood cultures (aOR 1.43, 95% CI 1.06-1.93) (Table 2), even when… Click to show full abstract
both CD and VD was coagulase negative Staphylococcus. Adjusting for confounders, CD remained an independent risk factor for positive blood cultures (aOR 1.43, 95% CI 1.06-1.93) (Table 2), even when stratifying by chorioamnionitis. Administration of latency antibiotics was protective (aOR 0.29, 95% CI 0.16-0.53). Notably, CDs were associated with a lower odds of gram negative aerobe colonization (aOR 1⁄4 0.47, 95% CI 0.25-0.92). CONCLUSION: CD was associated with an increased risk of positive neonatal blood cultures compared to VD. These findings suggest that MOD may modulate the microbial profile in neonates, and given the potential role of the microbiome in development of obesity, asthma, and allergies, may have longstanding impacts on child health. Further study is needed to understand if these changes persist beyond the newborn period.
               
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