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Graphical Abstract Through formulation screening, the irregular-shaped azilsartan nanocrystals were prepared and optimized by bead milling method and solidified by freeze-drying. The best formulation which had the size of 300 nm… Click to show full abstract
Graphical Abstract Through formulation screening, the irregular-shaped azilsartan nanocrystals were prepared and optimized by bead milling method and solidified by freeze-drying. The best formulation which had the size of 300 nm was expressed in its state by the studies of morphology and crystal from. And azilsartan nanocrystals showed its improvement about in-vitro dissolution and in-vivo bioavailability with physical mixture as reference. Unlabelled image
Keywords:
vitro vivo;
azilsartan nanocrystals;
azilsartan;
characterization vitro;
vivo evaluation;
optimization characterization
Journal Title: Asian Journal of Pharmaceutical Sciences
Year Published: 2017
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Journal Title: Asian Journal of Pharmaceutical Sciences
Year Published: 2017
Link to full text (if available)
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recommendations!