Graphical Abstract In the present work, the solubility data of silymarin (SM) in pure supercritical carbon dioxide (SCCO2) and SCCO2 with added cosolvent was measured at temperatures ranging from 308… Click to show full abstract
Graphical Abstract In the present work, the solubility data of silymarin (SM) in pure supercritical carbon dioxide (SCCO2) and SCCO2 with added cosolvent was measured at temperatures ranging from 308 to 338 K and pressures from 8 to 22 MPa. The experimental data were fit with three semi-empirical density-based models (Chrastil, Bartle and Mendez-Santiago and Teja models) and a back-propagation artificial neural networks (BPANN) model. Unlabelled image
               
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