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Preparation and toxicity evaluation of a novel nattokinase-tauroursodeoxycholate complex

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Graphical Abstract For improving the utilization of NK, a complex of NK-TUDCA to reduce the toxicity of intravenous NK injection, was designed by using NK as the cationic moiety and… Click to show full abstract

Graphical Abstract For improving the utilization of NK, a complex of NK-TUDCA to reduce the toxicity of intravenous NK injection, was designed by using NK as the cationic moiety and TUDCA as the anionic moiety. The NK-TUDCA reduced toxicity by the delayed release of NK from the complex and still possessed the inherent powerful efficiency of NK.Unlabelled image

Keywords: evaluation novel; toxicity evaluation; nattokinase tauroursodeoxycholate; novel nattokinase; toxicity; preparation toxicity

Journal Title: Asian Journal of Pharmaceutical Sciences
Year Published: 2018

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