LAUSR

As of May 1, 2020, coronavirus disease caused by infection by SARS-CoV-2 (COVID-19) has affected over 3 181 000 people worldwide and caused more than 220 000 deaths. Around 1% of cases occur in children under 10 years, most frequently with a mild course of disease. Cancer patients receiving chemotherapy could be more vulnerable to complications from COVID-19, as suggested by Liang and colleagues, but the evidence on paediatric cancer patients is scarce. We present the case of a boy aged 20 months that had received a diagnosis of high-risk B-cell acute lymphoblastic leukaemia with KMT2A-MLLT3 rearrangement 2 months prior. At the end of the second part of the induction phase, the patient developed febrile neutropenia in the absence of respiratory symptoms or any other sign of focal infection. Due to the high prevalence of COVID-19 in Spain, in addition to blood and urine cultures, the workup included a SARS-CoV2 test by real-time reverse transcription polymerase chain reaction (RT-PCR) in a nasopharyngeal swab sample, which was negative. We initiated empirical antibiotherapy with