LAUSR

Abstract The objective of this study was to quantify the flavonoids present in the Eugenia jambolana Lam extract and fractions, identify their composition by LC-MS, to determine the cytoprotective potential against aluminium Chloride toxicity in a prokaryotic and eukaryotic model, as well as the mechanism of cytoprotection of the extract and fractions. The ethanolic extract from E. jambolana, as well as its tannic and flavonoid fractions, were tested and the minimum bactericidal and fungicidal concentration of the products associated with aluminum chloride in different concentrations were established. These same products were used in the germination of lettuce seeds (Lactuva sativa). The extract and fractions did not show cytoprotective activity in bacterial and fungal models, since it was not able to interfere with the growth profile of these microorganisms. In relation to the vegetal model, it was possible to observe significant effects on caulis and lettuce radicle growth, as well as on the dry weight of radicles, showing a cytoprotective effect capable of inhibiting the aluminum chloride toxicity at different concentrations. In this way, due to the problems faced with aluminum contamination and the characteristics of the soils the E. jambolana extract may show an alternative to the toxicity of this metal.