LAUSR

Research Objectives To determine predictors of persistent neurobehavioral symptoms1 in adults with mild traumatic brain injury (mTBI)/concussion. Design Cohort Study. Setting Concussion clinic. Participants Adults with concussion (n=146; n=90 (61.6%) women). Interventions Not Applicable. Main Outcome Measures Behavioral Assessment Screening Tool (BAST): measures frequency of neurobehavioral symptoms (1=never to 5=very often) in five domains at 3-months post-baseline: Negative Affect, Fatigue, Executive Function, Impulsivity, and Substance Abuse.2-5 Baseline factors included as independent variables in all predictive models were: previous head injury (Y/N), loss of consciousness (LOC) (Y/N), preinjury psychiatric diagnosis (Y/N), time since injury, and age at first concussion. Results We conducted five linear regressions (one for each BAST subscale). Models were significant for Negative Affect (R2Adj =.148, p Conclusions Our research indicates that personal and injury-related factors are associated with persistent affective, fatigue, and cognitive symptoms, but not impulsivity or substance abuse. Identifying those at risk for persistent symptoms after mTBI/concussion at the time of their initial clinic visit could inform risk-stratified clinical surveillance and treatment planning. Author(s) Disclosures The authors report no conflicts of interest.