Abstract A potential host-derived probiotic, Bacillus pumilus A97, was successfully screened from 434 isolates from the intestines of healthy adult Trachinotus ovatus based on in vitro assays of non-haemolytic activity,… Click to show full abstract
Abstract A potential host-derived probiotic, Bacillus pumilus A97, was successfully screened from 434 isolates from the intestines of healthy adult Trachinotus ovatus based on in vitro assays of non-haemolytic activity, extracellular enzyme activity, inhibitory activity against pathogens (Vibrio or Streptococcus), tolerance to gastrointestinal stress and bile salts, cell surface hydrophobicity, autoaggregation, biofilm formation and antibiotic susceptibility. Dietary supplementation with B. pumilus A97 (1.0 × 108 CFU·g−1) for 56 days significantly improved the weight gain, specific growth rate, feed efficiency and non-specific immune responses of T. ovatus (P
               
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