Abstract The purpose of this study was to evaluate the dietary effects of Bacillus amyloliquefaciens COFCAU_P1 on immune-biochemical response, immune-related gene expression and resistance of Labeo rohita against A. hydrophila… Click to show full abstract
Abstract The purpose of this study was to evaluate the dietary effects of Bacillus amyloliquefaciens COFCAU_P1 on immune-biochemical response, immune-related gene expression and resistance of Labeo rohita against A. hydrophila infection. Fingerlings of L. rohita were fed with three B. amyloliquefaciens-supplemented diets (1 × 107, 1 × 108 and 1 × 109 cells g−1 of diet) for 30 days. Different innate immune parameters, biochemical responses and immune-related gene expression were measured at the end of the 10, 20 and 30 days of feeding. Control and test fish were challenged intraperitoneally by A. hydrophila after 30 days of experimental feeding. Mortality was observed and cumulative mortality percentage was calculated. The immunological (superoxide anion, myeloperoxidase and antiprotease) and biochemical (total protein, albumin and globulin) responses were significantly (p
               
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