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Image-based characterization of plaque lipid concentration changes in time and the role of statin therapy

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Results: 5 female SCAD patients and 9 healthy controls (C) were enrolled (age 45 9 vs 45 13years, pZ 0.95; BMI 21 3 vs 23 kg/mq, pZ 0.22; mean BP… Click to show full abstract

Results: 5 female SCAD patients and 9 healthy controls (C) were enrolled (age 45 9 vs 45 13years, pZ 0.95; BMI 21 3 vs 23 kg/mq, pZ 0.22; mean BP 77 5 vs 85 10 mmHg, pZ 0.053). 2nd interface peak was reduced in the SCAD group (97 29 130 19, pZ 0.04), whereas RMSE/ mean was increased (1.89 0.68 vs 0.97 0.30, pZ 0.02). Similar values were found for the 1 interface. IMT (0.165 0.031 vs 0.125 0.022mm, pZ 0.03), but not AT (0.095 0.020 vs 0.081 0.020mm, pZ 0.20) and IMAT (0.260 0.049 vs 0.206 0.030mm, pZ 0.053), was significantly higher in SCAD. Radial internal diameter and wall/lumen ratio were similar: conversely WCSA was increased in SCAD (1.69 0.48 vs 1.07 0.37mm, pZ 0.02). Conclusions: Radial arteries of SCAD patients were characterized by increased wall thickness. Furthermore, the 2 echogenic layer exhibited loss of echogenicity and inhomogeneity, features similar to FMD patients.

Keywords: image based; lipid concentration; based characterization; characterization plaque; concentration changes; plaque lipid

Journal Title: Artery Research
Year Published: 2017

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