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s 91 Conclusion: Oscillometric measurement of 24-hour pulse wave velocity is a simple and valid method and has an additional predictive value for all-cause mortality in elderly patients with end-stage renal disease. References [1] Sarafidis PA, Loutradis C, Karpetas A, Tzanis G, Piperidou A, Koutroumpas G, et al. Ambulatory Pulse Wave Velocity Is a Stronger Predictor of Cardiovascular Events and All-Cause Mortality Than Office and Ambulatory Blood Pressure in Hemodialysis Patients. Hypertension. 2017. [2] Van Bortel LM, Laurent S, Boutouyrie P, Chowienczyk P, Cruickshank J, De Backer T, et al. Expert consensus document on the measurement of aortic stiffness in daily practice using carotid-femoral pulse wave velocity. J Hypertens. 2012;30(3):445-448. P108 IMPACT OF KIDNEY TRANSPLANTATION ON AORTIC STIFFNESS INDEX b0 Marie-Pier Desjardins , Aboubacar Sidibé , Catherine Fortier , Fabrice Mac-Way , Sacha De Serres , Richard Larivière , Bart Spronck , Mohsen Agharazii 1 CHU de Québec Research Center, Hotel-Dieu de Québec hospital, Division of Nephrology, Université Laval, Québec City, Canada Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia Purpose/ Background/ Objectives: We have shown that aortic stiffness improves as early as 3 months post-kidney transplantation (KTx). Aortic stiffness index b0, a blood pressure independent parameter, has been proposed to be a better indicator of vascular wall property. This study was designed to examine 1) the early versus late changes in aortic stiffness index b0 and 2) to define the characteristics of patients with favourable and unfavourable trajectories of aortic stiffness index b0 after KTx. Methods: In 79 patients who underwent KTx, aortic stiffness was assessed before, 3, 6 and 24 months after KTx. Aortic stiffness was determined by carotid-femoral pulse wave velocity (cf-PWV), while aortic stiffness index b0 was obtained using a formulae proposed by Spronck and colleagues. Cytokines profile was measured in plasma by ELISA. Results: There was a reduction of b0 3 months after KTx (29.0 2.0 to 25.8 1.2, PZ 0.033). Then, aortic stiffness index b0 gradually increased at 6 (28.0 1.4, PZ 0.005 vs 3 months) and 24 months (28.3 1.3, PZ 0.003 vs 3 months). Unfavourable progression of b0 was not related to renal function, age, comorbidities or kidney donor characteristics. However, the unfavourable progression of b0 was associated with higher levels of interleukin-6 (PZ 0.029). Conclusions: The improvement of aortic stiffness index b0 3 months after KTx suggests that KTx leads to an early improvement of the intrinsic mechanical properties of aorta. However, this improvement is followed by a late progression of b0, which is associated with increased pro-inflammatory cytokine, suggesting that activation of immune system may be involved in arterial wall remodeling in kidney transplant recipients. P109 PROGRESSION OF AORTIC ARCH CALCIFICATION AFTER KIDNEY TRANSPLANT AND ITS IMPORTANCE IN PREDICTING CARDIOVASCULAR RISK: SINGLE-CENTER 2-YEAR FOLLOW-UP STUDY Agne Laucyte-Cibulskiene , Evelina Boreikaite , Gediminas Aucina , Migle Gudynaite , Ilona Rudminiene , Sigita Anisko , Loreta Vareikiene , Liutauras Gumbys , Nerijus Teresius , Dileta Valanciene , Ligita Ryliskyte , Laurynas Rimsevicius , Marius Miglinas , Kestutis Strupas 5 Centre of Nephrology, Vilnius University Hospital Santaros Clinics, Vilnius, Lithuania Faculty of Medicine, Vilnius University, Lithuania Centre of Radiology and Nuclear Medicine, Vilnius University Hospital Santaros Clinics, Vilnius, Lithuania Department of Cardiovascular Medicine, Vilnius University Hospital Santaros Clinics, Vilnius, Lithuania