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Comparing venous reconstructions and antimicrobial graft reconstructions in mycotic abdominal aortic aneurysms and aortic graft infections.

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INTRODUCTION The perioperative mortality and morbidity rates of surgical repair of mycotic abdominal aortic aneurysms and aortic graft infections are high and the appropriate treatment is debated. This retrospective study… Click to show full abstract

INTRODUCTION The perioperative mortality and morbidity rates of surgical repair of mycotic abdominal aortic aneurysms and aortic graft infections are high and the appropriate treatment is debated. This retrospective study compared venous and antimicrobial prosthetic aortic graft reconstructions. METHODS All patients of the Northwest Clinics and St. Antonius Hospital who were treated for mycotic abdominal aortic aneurysms or aortic graft infections between January 1, 2008, and January 1, 2018, were analyzed. Exclusion criterion was treatment other than venous or antimicrobial reconstructions. Primary end points were 30-day complications and mortality rates and 3-year overall survival. Secondary end points were reintervention-free survival, persistent infection and reinfection rates, and hospital length of stay. RESULTS Inclusion criteria resulted in 51 patients, of whom 32 underwent venous reconstructions and 19 antimicrobial prosthetic aortic graft reconstructions. Baseline characteristics did not differ significantly between these groups, except for duration of surgical repair, which was longer in the venous group. The 30-day and 1-year mortality rates, reinfection rates, complication rates, and hospital length of stay did not significantly differ between the groups. The 3-year overall survival was 77% for venous reconstruction compared with 66% for antimicrobial reconstruction (P = .781). The 30-day reintervention rate was 19% for the venous group compared with 42% for the prosthetic group (P = .071). Reintervention-free survival at 3 years was 46% for the venous group compared with 52% for the prosthetic group (P = .615). CONCLUSION Venous reconstruction tends to have better 3-year overall survival and lower 30-day reintervention rates compared with antimicrobial prosthetic graft reconstruction in patients with mycotic abdominal aortic aneurysms or abdominal aortic graft infections. In the acute setting, antimicrobial prosthetic graft reconstruction is a valuable solution due to the shorter operation time and similar 30-day mortality and complication rates.

Keywords: mycotic abdominal; graft; aortic aneurysms; aortic graft; abdominal aortic; graft infections

Journal Title: Annals of vascular surgery
Year Published: 2019

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