LAUSR

OBJECTIVE Increased use of endovascular repair for intact abdominal aortic aneurysms has fundamentally shifted the approach to ruptured aneurysms. Unfortunately, not all patients are anatomically suited for endovascular repair. It is hypothesized that, in the endovascular era, patients undergoing open repair are increasingly complex; with an unknown impact on post-operative morbidity and mortality. MATERIAL AND METHODS The Cleveland Clinic Foundation database was queried for all patients undergoing open repair of ruptured abdominal aortic aneurysms (rAAA) from 2006 to 2015. Electronic medical charts and cross-sectional imaging were retrospectively reviewed. The overall patient cohort was dichotomized between Early (E-OR, 2006 to 2010) and Late Open Repairs (L-OR, 2011 to 2015). Groups were compared based on demographic, anatomic and perioperative variables. The primary endpoint was perioperative mortality. Secondary endpoints included overall mortality, late aneurysm-related mortality and perioperative morbidity. RESULTS Of 140 patients who underwent open repair of rAAA (63, E-OR; 77, L-OR), 76% had cross-sectional imaging available for review. Aneurysm repairs in the later time period had significantly shorter infrarenal neck lengths, were more likely to have a prior aortic intervention, tended to have poor access vessels, and were more likely to require visceral or renal revascularization (each p<0.05). While late survival did not differ between time periods, perioperative mortality (27 vs 46%, p=0.021) and late aneurysm-related mortality (29.9% vs. 47.6%, p=0.031) was lower for L-OR compared with E-OR. While no anatomic variables significantly impacted survival, early time period of repair, presence of chronic kidney disease and need for cardiopulmonary resuscitation were predictive of both perioperative and overall mortality on univariate and multivariate analysis. CONCLUSIONS Despite the increasing anatomic and operative complexity of patients undergoing open repair of ruptured abdominal aortic aneurysms, perioperative mortality and late aneurysm-related mortality has improved over time. These results highlight the need for both systems and expertise needed to appropriately treat this changing patient population.