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Preservation of Heparin-Bonded Prosthetic Graft for Hemodialysis in the Setting of Early Heparin-Induced Thrombocytopenia.

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Heparin-bonded expanded polytetrafluoroethylene (ePTFE) grafts are increasingly used for dialysis access in lieu of standard ePTFE grafts to improve patency. Despite no established association between heparin-bonded graft placement and formation… Click to show full abstract

Heparin-bonded expanded polytetrafluoroethylene (ePTFE) grafts are increasingly used for dialysis access in lieu of standard ePTFE grafts to improve patency. Despite no established association between heparin-bonded graft placement and formation of platelet antibodies, cases of heparin-induced thrombocytopenia (HIT) have been observed after use of lower extremity heparin-bonded grafts, often resulting in their explantation. We report a rare case of HIT in the setting of recent heparin-bonded ePTFE arteriovenous graft placement and successful treatment of the condition with preservation of dialysis access.

Keywords: heparin; graft; heparin bonded; preservation; induced thrombocytopenia; heparin induced

Journal Title: Annals of vascular surgery
Year Published: 2020

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