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Symptomatic aortic mural thrombus treatment and outcomes.

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OBJECTIVES To report results achieved in treatment of symptomatic aortic mural thrombus in a single Institution. MATERIALS AND METHODS A retrospective analysis of data about 97 patients presenting with acute… Click to show full abstract

OBJECTIVES To report results achieved in treatment of symptomatic aortic mural thrombus in a single Institution. MATERIALS AND METHODS A retrospective analysis of data about 97 patients presenting with acute onset lower limb ischemia (Rutherford stage II-III), upper limb ischemia and mesenteric ischemia surgically treated between January 2011 and December 2018 in the Vascular and Endovascular Unit of Foch Hospital (Suresnes, France) was conducted. Only patients affected with primary aortic mural thrombus (PAMT) as source of embolism were included. RESULTS A total of 9 patients (mean age 51 years, range 28-69; 55.5%, n 5 male and 44.5% n 4 female) were affected with PAMT. Three (33.3%) patients presented a concomitant renal embolism (22.2% of acute renal failure). Thrombus was located at the level of thoracic aorta (4 patients), visceral aorta (2 patients) or infra-renal aorta (3 patients).PAMT was sessile or pedunculated in 5 (55.5%) and 4 (44.4%) patients respectively. Treatment consisted in anticoagulation in all patients in association with surgical exclusion of the PATM, distal thrombectomy alone or in addition to distal bypass. At a median follow-up of 22 months (range 1-57 months) no patients died, 4 patients (44.4%) recovered well and 5 patients (55.5%) experienced recurrence/thrombus persistency and needed secondary interventions. The best results and absence of recurrences were achieved in patients undergoing immediate exclusion of the PAMT. CONCLUSIONS PAMT is an uncommon source of embolism and no guidelines are at disposal in its management. An aggressive approach with anticoagulation and exclusion of thrombus seems to be efficacious in preventing recurrences limiting complications and optimizing outcomes.

Keywords: aortic mural; treatment; aorta patients; thrombus; mural thrombus; symptomatic aortic

Journal Title: Annals of vascular surgery
Year Published: 2020

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