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Intraluminal thrombus and abdominal aortic aneurysm complications.

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New techniques of CT digital subtraction angiographic imaging allow to study the aortic blood flow in case of abdominal aortic aneurysm and find unfavorable elements for a greater risk of… Click to show full abstract

New techniques of CT digital subtraction angiographic imaging allow to study the aortic blood flow in case of abdominal aortic aneurysm and find unfavorable elements for a greater risk of rupture. On the other hand, the intraluminal thrombus, whose growth is facilitated by a turbulent blood flow, damages the aneurysm walls through immune-inflammatory mechanisms, connected with release of proteases and specific metalloproteinases. Besides, the vasa vasorum thrombosis causes hypoxia in the aortic walls and, through a secondary production of oxygen reactive species, a proportional oxidative stress. Today, these pathological elements can be firstly researched with a Color Doppler US and CT angiography, but also with PET/CT to discover an inflammatory state. In addition, RMI can demonstrate a fragmented and laminated feature of the intraluminal thrombus, its high elastase content and correlated elastin reduction in the aneurysm medial layer. These data have not yet a mathematical translation.

Keywords: thrombus abdominal; intraluminal thrombus; aortic aneurysm; aneurysm complications; abdominal aortic

Journal Title: Annals of vascular surgery
Year Published: 2022

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