Highlights • IL-1β is a key proinflammatory cytokine involved in ischemic brain damage.• Administration of IL-1Ra improves the stroke outcome in young and co-morbid rats.• Acute IL-1Ra administration also promotes… Click to show full abstract
Highlights • IL-1β is a key proinflammatory cytokine involved in ischemic brain damage.• Administration of IL-1Ra improves the stroke outcome in young and co-morbid rats.• Acute IL-1Ra administration also promotes neurogenesis after experimental stroke.
               
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