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Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson’s disease

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Highlights • Evaluation of clinical parameters that could influence the success of cell therapy.• L-DOPA does not impair rodent graft viability.• L-DOPA treatment following transplantation can influence the host immune… Click to show full abstract

Highlights • Evaluation of clinical parameters that could influence the success of cell therapy.• L-DOPA does not impair rodent graft viability.• L-DOPA treatment following transplantation can influence the host immune response.• Cell transplant prior to initiation of L-DOPA treatment limits dyskinesia development.

Keywords: graft; dopa treatment; dopa; immune response; influence

Journal Title: Brain, Behavior, and Immunity
Year Published: 2017

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