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The effect of beta-adrenergic blockade on inflammatory and cardiovascular responses to acute mental stress

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Highlights • The mechanisms underlying acute stress-induced IL-6 responses are poorly understood.• We assessed the effects of beta-blockade with propranolol in a double-blind study.• Beta-blockade reduced IL-6 responses to stress… Click to show full abstract

Highlights • The mechanisms underlying acute stress-induced IL-6 responses are poorly understood.• We assessed the effects of beta-blockade with propranolol in a double-blind study.• Beta-blockade reduced IL-6 responses to stress in men but not women.• Blood pressure and heart rate responses was not affected by propranolol.• The study provides partial support for SNS involvement in stress-induced inflammation.

Keywords: adrenergic blockade; blockade inflammatory; beta; stress; effect beta; beta adrenergic

Journal Title: Brain, Behavior, and Immunity
Year Published: 2018

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