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Manufacturing Mesenchymal Stromal Cells for the Treatment of Graft-versus-Host Disease: A Survey among Centers Affiliated with the European Society for Blood and Marrow Transplantation

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Highlights • Seventeen EBMT centers participated to a questionnaire on MSC manufacturing.• 88% of centers manufacture MSC from bone marrow and only 2 centers from umbilical cord.• Human platelet lysate… Click to show full abstract

Highlights • Seventeen EBMT centers participated to a questionnaire on MSC manufacturing.• 88% of centers manufacture MSC from bone marrow and only 2 centers from umbilical cord.• Human platelet lysate has replaced bovine serum as culture medium supplement.• Release criteria extensively differ among centers.• The results highlight the need to harmonize MSC manufacturing.

Keywords: marrow; marrow transplantation; among centers; blood marrow

Journal Title: Biology of Blood and Marrow Transplantation
Year Published: 2018

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