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Three new ursane-type triterpenes (1-3) and twenty-one known triterpenoids (4-24) were isolated from the methanolic extract of the whole plants of Potentilla chinensis. Their structures were elucidated by extensive spectroscopic… Click to show full abstract
Three new ursane-type triterpenes (1-3) and twenty-one known triterpenoids (4-24) were isolated from the methanolic extract of the whole plants of Potentilla chinensis. Their structures were elucidated by extensive spectroscopic analysis of 1D and 2D NMR (HSQC, HMBC, COSY and ROESY) and HRESIMS data. The bioassay screening revealed the inhibitory effects on nitric oxide production of compounds 2, 5, 7, 9, 10, and 13-24 in LPS-induced RAW264.7 macrophages.
Keywords:
oxide inhibitory;
potentilla chinensis;
triterpenes nitric;
pentacyclic triterpenes;
nitric oxide
Journal Title: Bioorganic chemistry
Year Published: 2021
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Journal Title: Bioorganic chemistry
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!