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Clinically approved antidepressants modulate the brain’s emotional valence circuits, suggesting that the response of these circuits could serve as a biomarker for screening candidate antidepressant drugs. Here, we apply a… Click to show full abstract
Clinically approved antidepressants modulate the brain’s emotional valence circuits, suggesting that the response of these circuits could serve as a biomarker for screening candidate antidepressant drugs. Here, we apply a cross-validated predictive model to classify clinical state, emotional valence, and pharmacologic effect across eight task-based fMRI studies (n=306) of the effect of antidepressant administration on emotional face processing.
Keywords:
valence pharmacologic;
clinical state;
effect;
valence;
emotional valence;
state emotional
Journal Title: Biological Psychiatry
Year Published: 2018
Link to full text (if available)
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Journal Title: Biological Psychiatry
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!