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Understanding how tissue patterning emerges during embryogenesis is a long-standing goal of developmental biology. In particular, the complex interplay between extracellular and intracellular mechanical forces and biochemical cues that lead… Click to show full abstract
Understanding how tissue patterning emerges during embryogenesis is a long-standing goal of developmental biology. In particular, the complex interplay between extracellular and intracellular mechanical forces and biochemical cues that lead to cellular differentiation and ultimately adult tissue remains an active area of investigation. One of the main challenges has been that experimental methods that allow for the simultaneous measurement of mechanical force and biochemical signaling are limited.
Journal Title: Biophysical journal
Year Published: 2017
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