characterize the interplay between tumor cells and angiogenesis, as well as their proliferation, phenotypic transitions, and death. We use this model to predict– early in course of neoadjuvant therapy–the eventual… Click to show full abstract
characterize the interplay between tumor cells and angiogenesis, as well as their proliferation, phenotypic transitions, and death. We use this model to predict– early in course of neoadjuvant therapy–the eventual response of the individual patient. Success in this endeavor would enable replacing an ineffective treatment with an alternative regimen, thereby potentially improving outcomes and curtailing unnecessary toxicities. Furthermore, our approach can be applied to any disease site for which neoadjuvant therapy is indicated and the requisite data is accessible.
               
Click one of the above tabs to view related content.