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Short-latency afferent inhibition remains intact without cortical somatosensory input: Evidence from a patient with isolated thalamic infarct

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Short-latency afferent inhibition (SAI) is a transcranial magnetic stimulation (TMS) paradigm elicited by pairing a peripheral nerve electrical stimulation with TMS of the motor cortex. Therefore, SAI is suggested as… Click to show full abstract

Short-latency afferent inhibition (SAI) is a transcranial magnetic stimulation (TMS) paradigm elicited by pairing a peripheral nerve electrical stimulation with TMS of the motor cortex. Therefore, SAI is suggested as a neurophysiological marker of sensorimotor integrity and excitability [1]. Even though it is widely used in neurophysiological studies, the exact physiological mechanism that produces SAI still remains unclear. We report a case of thalamic infarction with an absent N20 component of somatosensory evoked potential (SEP). We aimed to evaluate neural circuits involved in SAI together with inadequate sensory input.

Keywords: latency afferent; short latency; somatosensory; afferent inhibition

Journal Title: Brain Stimulation
Year Published: 2021

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