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Steroids and anthraquinones from the deep-sea-derived fungus Aspergillus nidulans MCCC 3A00050

Abstract Aspergillus nidulans MCCC 3A00050 was isolated from a deep-sea sediment sample of the western Pacific Ocean. A systematic investigation on its chemical constituents led to the isolation of 19… Click to show full abstract

Abstract Aspergillus nidulans MCCC 3A00050 was isolated from a deep-sea sediment sample of the western Pacific Ocean. A systematic investigation on its chemical constituents led to the isolation of 19 compounds, including 13 steroids (1–13), four anthraquinones (14–17), one phenolics (18), and one chromanone (19). For the first time, three diosgenins (1–3) were isolated from fungi, three ergosterols (4–6) from the genus of Aspergillus, while other 11 miscellaneous compounds (7–11 and 14–19) from the species of Aspergillus nidulans. The isolation of diosgenins (1–3) and ergosterols (4–6) might be used as chemotaxonomic markers for the genus of Aspergillus and the species of Aspergillus nidulans, respectively.

Keywords: mccc 3a00050; aspergillus nidulans; steroids anthraquinones; nidulans mccc; deep sea

Journal Title: Biochemical Systematics and Ecology
Year Published: 2019

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