Highlights • The grapefruit osthole act as a natural inhibitor of HDACs.• Osthole inhibited the growth of A549 cells, in a time- and concentration-dependent manner.• Ostholeinduced apoptosis and the caspase-9… Click to show full abstract
Highlights • The grapefruit osthole act as a natural inhibitor of HDACs.• Osthole inhibited the growth of A549 cells, in a time- and concentration-dependent manner.• Ostholeinduced apoptosis and the caspase-9 was also increased by osthole treatment.
               
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