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Abstract A proof-of-concept method for measuring cardiac tissue contraction force using an in-house-developed piezoelectric cantilever sensor system is demonstrated. Contracting forces of 7.2–16.6 μN (n = 5) were measured from a human cardiac… Click to show full abstract
Abstract A proof-of-concept method for measuring cardiac tissue contraction force using an in-house-developed piezoelectric cantilever sensor system is demonstrated. Contracting forces of 7.2–16.6 μN (n = 5) were measured from a human cardiac tissue construct. Beating cardiac tissue constructs were monitored in-situ under a microscope during the contraction force measurements. Development of the measurement method allows very low forces such as the ones that appear in biological small scale systems to be determined.
Journal Title: Current Applied Physics
Year Published: 2020
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