Brain tumours constitute the second most common malignancy in children Click to show full abstract
Brain tumours constitute the second most common malignancy in children <15 years of age and the second most common cause of death in children [1]. Whereas supratentorial tumours are more common in children <3 years of age, posterior fossa tumours are more common in children 4-10 years old, and both locations are equally common in children after 10 years of age [2,3]. Clinical presentations depend on the location, size, and extent of the lesion, and are usually secondary to direct compression of underlying brain parenchyma, mass effect causing shift of intracranial contents, raised intracranial pressure, or focal cerebral ischemia. However, symptoms may be nonspecific and include headache, ataxia, nausea, vomiting, weakness, gait disturbance, seizures, torticollis, and visual or speech changes. Although usually insidious, acute presentations due to stroke or obstruction of cerebrospinal fluid flow can occur. In this paper, we review the imaging appearances and approach to the differential diagnosis of some of the common supratentorial and posterior fossa tumours in children, selected based either on high prevalence or aggressiveness. We provide a broad overview of the imaging features of these selected tumours, which a general radiologist in practice or resident in training is likely to come across, along with the most likely differentials for each, although this is by no means an exhaustive compilation.Where there are unique features in the
               
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