Nearly 140,000 Canadians live with epilepsy, and many suffer social stigma and economic disadvantage as a result [1]. For patients with medically refractory focal epilepsy, surgical resection of epileptogenic tissue… Click to show full abstract
Nearly 140,000 Canadians live with epilepsy, and many suffer social stigma and economic disadvantage as a result [1]. For patients with medically refractory focal epilepsy, surgical resection of epileptogenic tissue improves seizure control and offers the possibility of seizure freedom [2]. The presurgical workup of these patients involves a triangulation of seizure semiology, electroencephalographic data and neuroimaging data [3]. Magnetic resonance imaging (MRI) plays a critical role in the identification, localization, and characterization of epileptogenic lesions [4]. Patients with chronic focal epilepsy and an epileptogenic lesion identified by MRI have significantly better surgical outcomes, compared with patients who are considered MRI-negative [5,6]. Early use of MRI may also benefit many patients with a first seizure or new-onset epilepsy, as the information gained from MRI can aid in counseling, help with the decision to start antiepileptic drug therapy, and expedite referral for epilepsy surgery when appropriate [7]. MRI has been reported to detect abnormalities in 74% of patients suffering from medically refractory focal epilepsy [8]. The detection rate in this population may be as high as 91% with the use of dedicated epilepsy imaging protocols that are interpreted by experienced neuroradiologists who work at epilepsy referral centres and have access to clinical information about the seizure semiology [9]. One would expect the detection rate to be lower in the relatively undifferentiated group of patients presenting with a first
               
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