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Structured interlocked-microcapsules: A novel scaffold for enzyme immobilization

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Abstract A facile approach to prepare structured interlocked-microcapsules (SIMC) was developed, which combined the advantages of open mouthed structure, hierarchical porous nanostructure and interlocked architecture. The specific surface area of… Click to show full abstract

Abstract A facile approach to prepare structured interlocked-microcapsules (SIMC) was developed, which combined the advantages of open mouthed structure, hierarchical porous nanostructure and interlocked architecture. The specific surface area of SIMC was 374.6 m 2 /g and the diameter of the pores was 8.707 nm. Nitrile hydratase (NHase) was immobilized on SIMC via covalent bonding to realize the easy separation of the enzyme and improve properties of enzyme such as pH tolerance and heat stability. This work demonstrated that the enzyme-immobilized SIMC presented high catalytic performance and significantly improved stability.

Keywords: enzyme immobilization; scaffold enzyme; novel scaffold; interlocked microcapsules; microcapsules novel; structured interlocked

Journal Title: Catalysis Communications
Year Published: 2017

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