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Au-catalyzed domino process synthesis of imidazo[1,2-a]pyridines from 2-aminopyridine and N-tosylhydrazones: An efficient CN bond formation reaction

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Abstract A novel Au-catalyzed domino reaction for the synthesis of imidazo[1,2- a ]pyridines from 2-aminopyridine and N-tosylhydrazones has been developed using molecular oxygen. It represents a new strategy for the… Click to show full abstract

Abstract A novel Au-catalyzed domino reaction for the synthesis of imidazo[1,2- a ]pyridines from 2-aminopyridine and N-tosylhydrazones has been developed using molecular oxygen. It represents a new strategy for the formation of C N bonds. This transformation demonstrated a broad tolerance toward the substrates and allowed the generation of a diverse imidazo[1,2- a ]pyridine derivatives with good yields.

Keywords: aminopyridine tosylhydrazones; pyridines aminopyridine; catalyzed domino; synthesis imidazo; imidazo pyridines

Journal Title: Catalysis Communications
Year Published: 2017

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