LAUSR

Abstract In this work, we demonstrate that solid-base such as amino-modified silica aerogel (SA-NH2) together with trace water showed excellent catalytic performance in one-pot sequential reaction of acid-catalyzed benzaldehyde dimethyl acetal hydrolysis and base-catalyzed Henry reaction which was usually catalyzed by acid-base bifunctional heterogeneous catalyst. The role of trace water in the reaction was discussed by batch control experiment. This SA-NH2/water catalytic system showed high reactant conversions (> 99%) and main product selectivities (up to 99.4%). The trace water induced acid catalysis mechanism and a possible H+/-NH2 coexistence mechanism were given to explain the synergistic catalytic effect of solid-base and trace water.