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Abstract A novel chitosan-supported cinchona urea heterogeneous catalyst was developed for asymmetric reaction. The catalytic activity of the chitosan-supported organocatalyst was examined in the asymmetric Michael addition reaction to give… Click to show full abstract
Abstract A novel chitosan-supported cinchona urea heterogeneous catalyst was developed for asymmetric reaction. The catalytic activity of the chitosan-supported organocatalyst was examined in the asymmetric Michael addition reaction to give chiral adducts in good yields with excellent enantioselectivities (up to 99% ee). The insolubility of the chitosan-supported cinchona urea catalyst facilitated catalyst recovery. The catalyst was easily separated and reused without any loss in catalytic activity.
Journal Title: Catalysis Communications
Year Published: 2020
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