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Pheochromocytomas and Paragangliomas, Genetically Diverse and Minimalist, All at Once!

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Pheochromocytomas and paragangliomas are infrequent, genetically heterogeneous neuroendocrine tumors. In this issue of Cancer Cell, Fishbein et al. report novel driver genes, pathogenic mechanisms, and markers of malignancy. Notably, the new… Click to show full abstract

Pheochromocytomas and paragangliomas are infrequent, genetically heterogeneous neuroendocrine tumors. In this issue of Cancer Cell, Fishbein et al. report novel driver genes, pathogenic mechanisms, and markers of malignancy. Notably, the new findings support the long-held view that these tumors distinctively arise from a single driver event, either inherited or acquired.

Keywords: paragangliomas genetically; diverse minimalist; genetically diverse; pheochromocytomas paragangliomas

Journal Title: Cancer cell
Year Published: 2017

Link to full text (if available)


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