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Genetic Alterations Impact Immune Microenvironment Interactions in Follicular Lymphoma.

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Interactions between germinal center B cells and immune cells in the microenvironment can play integral roles in transformation and growth of follicular lymphoma (FL). Three recent studies, two in this… Click to show full abstract

Interactions between germinal center B cells and immune cells in the microenvironment can play integral roles in transformation and growth of follicular lymphoma (FL). Three recent studies, two in this issue of Cancer Cell and one in Cell Reports, elucidate how genetic alterations in CTSS and EZH2 impact these interactions, with implications for FL immunotherapy.

Keywords: follicular lymphoma; genetic alterations; immune microenvironment; impact immune; alterations impact

Journal Title: Cancer cell
Year Published: 2020

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