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Gluing Proteins for Targeted Degradation.

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Targeted protein degradation is an emerging technology for drug development. An article published in Nature reported a novel mechanism of targeted protein degradation triggered by small-molecule-induced polymerization of the oncogenic… Click to show full abstract

Targeted protein degradation is an emerging technology for drug development. An article published in Nature reported a novel mechanism of targeted protein degradation triggered by small-molecule-induced polymerization of the oncogenic transcription factor BCL6.

Keywords: degradation; proteins targeted; targeted degradation; gluing proteins

Journal Title: Cancer cell
Year Published: 2021

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