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A large-scale snapshot of intratumor heterogeneity in human cancer.

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Using sophisticated statistical analyses on population-scale cancer whole-genome sequences, a new study published in Cell characterizes the genomic architecture of intratumor heterogeneity (ITH). It results in an unprecedented snapshot of… Click to show full abstract

Using sophisticated statistical analyses on population-scale cancer whole-genome sequences, a new study published in Cell characterizes the genomic architecture of intratumor heterogeneity (ITH). It results in an unprecedented snapshot of subclones in about 30 cancer types, generating a wealth of insight into the underlying mutational events, processes, and their selection.

Keywords: cancer; large scale; scale snapshot; intratumor heterogeneity

Journal Title: Cancer cell
Year Published: 2021

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