Cardiac resynchronization therapy (CRT) improves cardiac mechanics and quality of life in many patients with evidence of electromechanical cardiac dyssynchrony. However, up to 30% of patients receiving CRT do not… Click to show full abstract
Cardiac resynchronization therapy (CRT) improves cardiac mechanics and quality of life in many patients with evidence of electromechanical cardiac dyssynchrony. However, up to 30% of patients receiving CRT do not respond to therapy. The mediator for poor response likely varies among patients; however, careful evaluation of mechanical dyssynchrony may inform management strategies. In this article, some of the methods and supporting evidence for dyssynchrony assessment with MRI as a predictor for CRT response are presented. The case is made for pre-implant assessment with MRI because of its ability to characterize scar, coronary venous distribution, and regional strain patterns.
               
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