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Abstract We report herein the design and synthesis of a series of novel nitrobenzamide derivatives. Results reveal that many of them display considerable in vitro antitubercular activity. Four N-benzyl or… Click to show full abstract
Abstract We report herein the design and synthesis of a series of novel nitrobenzamide derivatives. Results reveal that many of them display considerable in vitro antitubercular activity. Four N-benzyl or N-(pyridine-2-yl)methyl 3,5-dinitrobenzamides A6, A11, C1 and C4 have not only the same excellent MIC values of 1500), opening a new direction for further development.
Keywords:
synthesis antimycobacterial;
design synthesis;
nitrobenzamide derivatives;
antimycobacterial activity;
novel nitrobenzamide
Journal Title: Chinese Chemical Letters
Year Published: 2019
Link to full text (if available)
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Journal Title: Chinese Chemical Letters
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!