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Recent advances on iron-catalyzed coupling reactions involving organolithium reagents

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Abstract Owing to their inexpensive and environmentally friendly properties, iron-based catalysts have been actively investigated for new organic reactions. In this account, we summarized our recent results on iron-catalyzed cross-coupling… Click to show full abstract

Abstract Owing to their inexpensive and environmentally friendly properties, iron-based catalysts have been actively investigated for new organic reactions. In this account, we summarized our recent results on iron-catalyzed cross-coupling reactions and homo-coupling reactions. With iron-based catalysts, we constructed diverse carbon-carbon bonds, i.e., C(sp2)−C(sp3), C(sp3)−C(sp3), C(sp3)−C(sp2) and C(sp2)−C(sp2) bonds. In order to demonstrate the usefulness of our iron protocol, we also carried out these reactions on gram-scale reactions, leading to good yields

Keywords: iron catalyzed; catalyzed coupling; sp3 sp3; recent advances; advances iron; coupling reactions

Journal Title: Chinese Chemical Letters
Year Published: 2019

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