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Abstract A Sc(OTf)3-catalyzed [3 + 3] cycloaddition of 2,2′-diester aziridines with β-(indol-2-yl)-α,β-unsaturated ketones was developed, affording polysubstituted tetrahydro-γ-carbolines in single diastereoisomers in good to excellent yields. Click to show full abstract
Abstract A Sc(OTf)3-catalyzed [3 + 3] cycloaddition of 2,2′-diester aziridines with β-(indol-2-yl)-α,β-unsaturated ketones was developed, affording polysubstituted tetrahydro-γ-carbolines in single diastereoisomers in good to excellent yields.
Keywords:
tetrahydro carbolines;
diester aziridines;
unsaturated ketones;
aziridines indol;
cycloaddition diester;
indol unsaturated
Journal Title: Chinese Chemical Letters
Year Published: 2020
Link to full text (if available)
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Journal Title: Chinese Chemical Letters
Year Published: 2020
Link to full text (if available)
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recommendations!