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Abstract Sulfoxonium ylides as carbene precursors couple smoothly with thioureas in the presence of 5 mol% of rhodium(II) acetate dimmer via carbenoid insertion to afford the corresponding 2-aminothiazoles with high chemoselectivity,… Click to show full abstract
Abstract Sulfoxonium ylides as carbene precursors couple smoothly with thioureas in the presence of 5 mol% of rhodium(II) acetate dimmer via carbenoid insertion to afford the corresponding 2-aminothiazoles with high chemoselectivity, providing a facile and efficient approach to access a variety of 2-aminothiazole derivatives with good functional groups tolerance.
Keywords:
sulfoxonium ylides;
synthesis aminothiazoles;
carbenoid insertion;
rhodium
Journal Title: Chinese Chemical Letters
Year Published: 2021
Link to full text (if available)
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Journal Title: Chinese Chemical Letters
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!