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Real-time identification of gut microbiota with aminopeptidase N using an activable NIR fluorescent probe

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Abstract A NIR fluorescent probe (DDAA) derived from fluorophore DDAO with alanine as the recognition group was developed for sensing aminopeptidase N (APN) in gut microbiota. Using DDAA as the… Click to show full abstract

Abstract A NIR fluorescent probe (DDAA) derived from fluorophore DDAO with alanine as the recognition group was developed for sensing aminopeptidase N (APN) in gut microbiota. Using DDAA as the real-time guidance tool for the fluorescence imaging of intestinal microorganism, target bacteria and saccharomycete possessing active APN were identified successfully from human feces.

Keywords: gut microbiota; nir fluorescent; real time; fluorescent probe

Journal Title: Chinese Chemical Letters
Year Published: 2021

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