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ER-mitochondria tethering and Ca2+ crosstalk: The IP3R team takes the field.

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Inter-organelle communication represents a booming topic in cell biology research, with endoplasmic reticulum (ER)-mitochondria coupling playing the lion's share. In a recent work, Bartok and colleagues found that inositol trisphosphates… Click to show full abstract

Inter-organelle communication represents a booming topic in cell biology research, with endoplasmic reticulum (ER)-mitochondria coupling playing the lion's share. In a recent work, Bartok and colleagues found that inositol trisphosphates receptors (IP3Rs), in addition to their well-known involvement in ER-mitochondria Ca2+ transfer, are endowed with structural properties at organelles' interface.

Keywords: ca2 crosstalk; mitochondria; mitochondria tethering; tethering ca2; ip3r team; crosstalk ip3r

Journal Title: Cell calcium
Year Published: 2019

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