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During development, disease or in response to changes in local environmental and/or nutrient supply, cellular metabolism is substantially remodeled. Reduced mitochondrial Ca2+ uptake was recently reported to induce metabolic remodeling,… Click to show full abstract
During development, disease or in response to changes in local environmental and/or nutrient supply, cellular metabolism is substantially remodeled. Reduced mitochondrial Ca2+ uptake was recently reported to induce metabolic remodeling, which through stimulating alterations in the epigenome causes changes in gene expression associated with fibroblast to myofibroblast differentiation.
Keywords:
directs fibrosis;
lamety directs;
mitochondrial ca2;
ca2 lamety
Journal Title: Cell calcium
Year Published: 2019
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Journal Title: Cell calcium
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!