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Cytosolic Ca2+ oversees the MASs production of pyruvate for the mitochondrial market.

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It is generally accepted that mitochondrial Ca2+ controls the pace of mitochondrial bioenergetics and thus ATP production. Szibor et al. challenge this paradigm, proposing that the balance between ATP consumption… Click to show full abstract

It is generally accepted that mitochondrial Ca2+ controls the pace of mitochondrial bioenergetics and thus ATP production. Szibor et al. challenge this paradigm, proposing that the balance between ATP consumption and production depends on mitochondrial pyruvate supply via the malate-aspartate shuttle (MAS) and is controlled by cytosolic Ca2+.

Keywords: oversees mass; ca2 oversees; production; ca2; cytosolic ca2; mass production

Journal Title: Cell calcium
Year Published: 2020

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