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Wolfram syndrome is a rare genetic disorder characterized by endocrine dysfunction and progressive neurodegeneration. By targeting intracellular calcium dysregulations, a sigma-1 receptor agonist rescued neurological deficits in preclinical models of… Click to show full abstract
Wolfram syndrome is a rare genetic disorder characterized by endocrine dysfunction and progressive neurodegeneration. By targeting intracellular calcium dysregulations, a sigma-1 receptor agonist rescued neurological deficits in preclinical models of Wolfram syndrome.
Keywords:
boosting mitochondria;
wolfram syndrome;
calcium;
calcium transfer;
mitochondria calcium
Journal Title: Cell calcium
Year Published: 2022
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Journal Title: Cell calcium
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!