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The survival rate of patients with ST-Segment elevation myocardial infarction treated with primary percutaneous coronary intervention and thrombolysis

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Abstract Background Cardiovascular diseases are the leading cause of death worldwide, and myocardial infarction is one of the common manifestations of these diseases. The goal of this study was to… Click to show full abstract

Abstract Background Cardiovascular diseases are the leading cause of death worldwide, and myocardial infarction is one of the common manifestations of these diseases. The goal of this study was to compare the survival rate of patients treated with thrombolysis and PPCI in patients with STEMI. Method This was a survival analysis study performed on 354 patients in Shiraz, Iran. Admission time was considered as the starting point and the time of death or the last follow-up time as the endpoint. All cases of STEMI patients were reviewed from the beginning to the end of 2018. Data were collected using a checklist and telephone call and they were analyzed using the Log Rank test, Kaplan-Meier and Cox regression models. Results The overall survival rate of patients in the PPCI group (92.4%) was significantly higher than that of the thrombolysis group (83.9%). The variables such as age, gender, diabetes history and type of treatment had an impact on the risk of death. After controlling the confounding factors, only the patients' age had a significant effect on death (HR: 1.05, P = 0.001, 95% CI: 1.02–1.09). Conclusions The survival rate of the PPCI group was higher than thrombolysis group. However, the difference in the criteria used to select the type of treatment may have a distorting effect on the subject. Therefore, it seems necessary to carry out studies with a more appropriate design.

Keywords: death; rate patients; myocardial infarction; survival rate; thrombolysis; rate

Journal Title: Clinical Epidemiology and Global Health
Year Published: 2020

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