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Non-mendelian Inheritance in Mammals Is Highly Constrained

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In this issue, Kazachenka, Bertozzi, and colleagues identify elements in the mouse genome with epigenetic variability between littermates, a phenomenon linked to transmission of phenotypes over generations. This addresses two… Click to show full abstract

In this issue, Kazachenka, Bertozzi, and colleagues identify elements in the mouse genome with epigenetic variability between littermates, a phenomenon linked to transmission of phenotypes over generations. This addresses two questions that remained unanswered despite intense speculation: how prevalent are these alleles, and what is their effect, within and across generations?

Keywords: mammals highly; non mendelian; highly constrained; inheritance mammals; mendelian inheritance

Journal Title: Cell
Year Published: 2018

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